Yes. You can update the group number for an enabled carrier integration after its initial configuration. You can change it again later by following the same steps.
Who can update a group number?
General Agency, Agency, Broker, and Service Team Member users who can access Carrier Exchange can update a group number. Service Team Members with read-only access can view the group number but cannot select it to edit.
To update a group number:
The group number is editable only when the carrier integration is enabled. If you need to locate the correct number before changing it, see Where do I find a group number for a carrier?.